1. Adaptability to difficult dosage forms
Difficult dosage forms usually include light-sensitive drugs, oxygen-sensitive preparations, complex multi-component mixtures, etc. The packaging requirements of these drugs are relatively demanding. The performance of HPMC capsules enables it to show unique advantages under these special requirements.
Protection of light-sensitive drugs
Many drugs are easily degraded under light, resulting in inactivation of active ingredients and affecting the therapeutic effect. HPMC capsules, due to their light stability, can effectively block light damage, protect the active ingredients of light-sensitive drugs, and ensure the stability of drugs throughout the shelf life. In addition, the transparency of HPMC capsules makes it visually attractive to consumers without affecting the protective effect of drugs.
Barrier effect on oxygen and moisture
Some drugs are particularly susceptible to oxygen and moisture, which may lead to degradation or failure of the drugs. HPMC capsules have good gas and moisture barrier properties due to their compact molecular structure, which can effectively prevent the external environment from damaging the drugs.
2. Excellent physical and chemical stability
HPMC capsules are also essential in packaging of difficult dosage forms. This stability stems from its unique molecular structure and material properties.
High and low temperature adaptability
Many difficult dosage forms may face temperature changes during transportation and storage. HPMC capsules have thermal stability, can maintain structural integrity over a wide temperature range, and are not easy to soften or brittle.
Chemical stability
HPMC capsules are also very resistant to a variety of chemicals. Compared with gelatin capsules, HPMC capsules are not easily affected by common chemicals, and can effectively protect the stability and activity of drug ingredients and avoid drug degradation caused by chemical reactions.
3. Flexible design and customization
The manufacturing process of HPMC capsules is highly controllable and flexible, and can be customized according to the specific needs of the drug. This feature enables HPMC capsules to meet the unique requirements of different difficult dosage forms.
Adjustment of capsule size and wall thickness
By adjusting the size and wall thickness of the capsule, pharmaceutical companies can optimize the release characteristics and bioavailability of the drug. This flexibility not only improves the therapeutic effect of the drug, but also enhances the patient's medication experience. For example, for drugs that require sustained or controlled release, manufacturers can design corresponding capsules to achieve the drug release rate.
Implementation of multiple release mechanisms
The design of HPMC capsules can also achieve multiple release mechanisms, such as delayed release, targeted release, etc. This provides rich possibilities for the development of difficult dosage forms, allowing pharmaceutical companies to develop more personalized drug solutions based on the actual needs of patients.
HGCAPS is a professional Empty Capsules Manufacturers. We offers a vertically integrated supply chain model to ensure reliable long-term supply, complete traceability and superior quality of raw materials.
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