Jan 20,2023

　　At present, empty hard capsules are a relatively common filling dosage form among health food contract manufacturers. Empty hard capsules occupy a relatively large market share, second only to tablets, and the market has a bright future. After years of application accumulation, it has mature packaging production experience, and it is also very easy to be accepted by consumers in the market. The main molding material of empty hard capsules on the market is gelatin. Bone gelatin made from bones is hard and brittle, while pig gelatin made from pig skin has good plasticity. It is ideal to mix gelatin with bone and skin. To increase its toughness and plasticity, an appropriate amount of glycerin, sorbitol, sodium carboxymethylcellulose, etc. can be added; to reduce its fluidity and increase jelly force, thickener agar, etc. can be added; some are sensitive to light For ingredients, opacifying agent titanium dioxide (2%-3%) can be added; to increase the appearance and easy to distinguish, coloring agents allowed by GB2760 such as bright blue, lemon yellow, and carmine can be added; to prevent mildew in the capsule, antiseptic can be added agent, etc.

　　Empty hard capsules are easy to accept by consumers because of their smooth and beautiful appearance, which can mask the inappropriate bitterness and odor of raw materials; the bioavailability of functional factors is high, and the amount of excipients is small. In the preparation process, no binder or pressure can be added, so it disintegrates quickly in the gastrointestinal tract. Generally, it can disintegrate and release functional substances within 3-10 minutes after taking it. Compared with pills and tablets, empty hard capsules have a Quick effect, good absorption; good stability. For example, vitamins should be packed in opaque empty hard capsules for easy storage; they can prolong the release of healthcare functional substances. The raw materials are first made into granules, then coated with materials with different release rates, mixed in proportion, and filled into empty capsules to achieve the purpose of prolonging the effect and many other advantages, which are more and more popular among domestic and foreign consumers.

　　In addition to gelatin capsules, there are vegetable capsules on the market now. Empty HPMC capsules are currently the best substitute for gelatin empty capsules, and they have also been used in many domestically marketed products. Because HPMC Red Heart Capsule is of plant origin, it provides a better solution for vegetarians.