Mar 04,2022

Enteric capsules are capsules that are insoluble in gastric juices, but disintegrate in intestinal juices to release the active ingredient. Because some drugs are highly irritating to the stomach and have harmful effects, they are not harmful to the intestines. So for this part of the drug, enteric-coated capsules should be made.

The shells of enteric capsules are added with special pharmaceutical polymer materials or treated to make them insoluble in gastric juice, and only disintegrate and dissolve in intestinal juice to release the active ingredients.

1. Principle

Enteric capsules use drug delivery technology to release the drug in the small intestine and large intestine, so that the drug can play a local or systemic therapeutic effect in the human intestine.

2. Kinds

Small enteric capsules (ie ordinary enteric capsules)

Colonic capsules

3. Advantages

(1) Small enteric capsules

①It can avoid the stimulation of the stomach after the drug is taken orally, so it can reduce the side effects of some drugs on the stomach;

②It can prevent the degradation of drugs that are unstable to acid or gastric enzymes in the stomach, thereby improving the efficacy of the drug:

③It can control the release site of the drug, so that the drug can be effectively absorbed in the small intestine.

(2) Colonic capsules

The advantages of colonic enteric capsules (colon-targeted drug delivery vehicles) are:

①Avoid the absorption of drugs in the stomach and small intestine, and reduce a series of side effects caused by the absorption of drugs in the stomach and small intestine;

②Increase the local concentration of the drug in the large intestine, so that the drug can give full play to the local therapeutic effect;

③It can reduce gastrointestinal irritation or side effects on the upper gastrointestinal tract of certain drugs;

④It can avoid the degradation of some drugs in the stomach and small intestine, and make the oral application of protein or peptide drugs possible.

In addition, the colonic capsules are more convenient to take than the enema method and are easily accepted by patients; the distribution of the drug in the colon is wider and more uniform; the drug can be widely distributed in the cecum, colon, transverse colon, descending colon and sigmoid colon, etc. advantage.

For more product information, click here: Enteric Capsules Wholesale.