1. Prevent drug degradation in the stomach
The improvement of bioavailability depends largely on the stability of drugs in the body. Many drugs are easily decomposed or lose their activity in the strong acid environment of the stomach, especially some acid-sensitive drugs, such as antibiotics, hormone drugs and some protein drugs. Enteric Capsules can effectively prevent the premature release of drugs in the stomach through its acid-resistant coating design, avoid drug degradation in the gastric acid environment, and thus protect the integrity and activity of drugs.
2. Promote effective absorption of drugs in the small intestine
The small intestine is the main site of drug absorption, where drugs enter the blood circulation through intestinal epithelial cells. Therefore, ensuring that drugs can be effectively released in the small intestine is the key to improving their bioavailability. Enteric Capsules can ensure that drugs are released directly into the small intestine after passing through the stomach through their enteric coating design. This process not only protects the activity of the drug, but also optimizes its absorption efficiency in the small intestine.
3. Improve the stability of drugs
Bioavailability is not only related to the absorption efficiency of drugs in the body, but also closely related to the stability of drugs. Many drugs may degrade when passing through the gastrointestinal tract due to contact with acidic substances or other ingredients, thus affecting their efficacy. The design of Enteric Capsules isolates the drug from the gastric acid environment through an enteric coating, effectively preventing the drug from having adverse reactions with other chemicals and improving the stability of the drug.
4. Reduce the first-pass effect of drugs
Many oral drugs undergo a metabolic process in the liver before reaching the systemic circulation. This process is called the "first-pass effect". During this process, some drugs may be metabolized and degraded, thereby reducing their effective concentration and affecting their bioavailability. Enteric Capsules release drugs in specific parts of the intestine, reducing the residence time of drugs in the stomach and upper digestive tract, thereby reducing the risk of premature metabolism of drugs.
5. Improve patient compliance
Patient compliance is crucial to the effectiveness of drug treatment. Enteric Capsules reduce gastric discomfort and side effects caused by drugs in the stomach through its enteric design. For example, some drugs may cause gastric irritation, nausea or discomfort if released in the stomach, and Enteric Capsules can avoid this, thereby improving patients' medication compliance.
HGCAPS is a professional Empty Capsules Manufacturers. We offers a vertically integrated supply chain model to ensure reliable long-term supply, complete traceability and superior quality of raw materials.
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