Nov 08,2024

The Need to Protect Sensitive Ingredients
Many nutritional supplements and pharmaceutical products contain ingredients that are extremely sensitive to the environment, such as plant extracts, antioxidants, vitamins, and certain active pharmaceutical ingredients. These ingredients are often susceptible to degradation by external factors (such as oxygen, moisture, heat, and light), resulting in reduced effectiveness and safety. In order to ensure that these sensitive ingredients do not degrade throughout their shelf life, effective protection measures must be taken to ensure that they can fully function in the body.

Excellent Oxygen Barrier Performance of Pullulan Capsules
The oxygen barrier performance of Pullulan Capsules is one of its core advantages in protecting sensitive ingredients. Studies have shown that the oxygen barrier capacity of Pullulan Capsules is 250 times higher than that of HPMC capsules and 9 times higher than that of traditional gelatin capsules. Oxygen is one of the main factors that cause the degradation of many sensitive ingredients, especially plant extracts, antioxidants, and other active ingredients, which undergo oxidation reactions when exposed to oxygen, causing them to lose their original effects.

Chemical inertness prevents cross-linking reactions
In addition to its oxygen barrier properties, Pullulan capsules’ chemical inertness is also an important feature that helps protect sensitive ingredients. Unlike traditional gelatin and HPMC capsules, Pullulan capsules are not susceptible to cross-linking reactions with the active ingredients inside the capsule. Cross-linking reactions refer to chemical reactions between the capsule and the contents, which may cause degradation or failure of the capsule material.

Pullulan capsules are able to avoid this problem due to their high chemical stability, ensuring that the sensitive ingredients inside the capsule are protected from external factors throughout the shelf life.

Protection from moisture and light
In addition to oxygen, moisture and light are also important factors that can cause sensitive ingredients to degrade. In addition to its extremely strong oxygen barrier capabilities, Pullulan capsules are also effective in resisting moisture penetration, further protecting the ingredients inside the capsule from environmental moisture. In addition, the material of Pullulan capsules is not easy to transmit light, which helps protect light-sensitive ingredients from degradation when exposed to light.

Application areas: from plant extracts to active pharmaceutical ingredients
Due to its protection of sensitive ingredients, Pullulan capsules are widely used in the preparation of various nutritional supplements and pharmaceuticals. In the field of plant extracts, many active ingredients of herbal plants (such as flavonoids, phenolic compounds, etc.) are easily inactivated when exposed to oxygen or light, and the protective effect of Pullulan capsules can effectively delay the degradation process of these ingredients, ensuring that their active ingredients can exert their effects when taken.

In the pharmaceutical field, many active pharmaceutical ingredients are also highly sensitive to environmental factors, especially some chemicals with strong antibacterial and antiviral effects. If they are not protected, they are easy to lose their effectiveness during storage. Pullulan capsules can protect these active ingredients from environmental influences through their powerful barrier function, ensuring the efficacy of the drugs.